Qualitative Phytochemical Screening and Toxicity Levels of Some Medicinal Plants Using Drosophila Melanogaster

Authors

  • Musa Nura Umar Science Laboratory Technology Department, Federal Polytechnic, P.M.B. 0231, Bauchi - Nigeria. Author
  • Kobbe Amina Isa Science Laboratory Technology Department, Federal Polytechnic, P.M.B. 0231, Bauchi - Nigeria. Author
  • Umar Abdullahi Science Laboratory Technology Department, Federal Polytechnic, P.M.B. 0231, Bauchi - Nigeria. Author
  • Shitu Faisal Abdullahi General Studies Department, Federal Polytechnic, P.M.B. 0231, Bauchi - Nigeria. Author

Keywords:

Maceration, Phytochemicals, Lethal, Toxicity, Medicinal Plants

Abstract

Three (3) selected plant samples were obtained and effectively extracted through maceration utilizing three distinct solvents, N-haxane, Chloroform, and Ethanol, in that order of increasing polarity. Boswellia dalzielli (bark), Gueira senegalensis(roots), and Annona squamosa L(leaves). The samples were labeled A, B, and C. After being extracted, the samples underwent some preliminary phytochemical screening in order to assess the plant bioactivity. Based on the results of the phytochemical analysis, sample C had high to moderate levels of phytochemicals in all three solvents; samples A and B also had moderate to low levels of phytochemicals in ethanol and chloroform, but sample A had low levels of those phytoconstituents in n-hexane. Toxicity studies were evaluated for all the extract and lethal doses at 50% (LD50) were analyzed and these are A (699.3mg/10g), B (284.9mg/10g), and C (759.8mg/10g). This result is expected to guide the traditional healers when using such plant for administration.

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Published

2024-05-31

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Articles

How to Cite

Musa Nura Umar, Kobbe Amina Isa, Umar Abdullahi, & Shitu Faisal Abdullahi. (2024). Qualitative Phytochemical Screening and Toxicity Levels of Some Medicinal Plants Using Drosophila Melanogaster. Journal of Health, Wellness and Safety Research, 4(3). https://hummingbirdjournals.com/jhwsr/article/view/159

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